| State | AVA | Climate | Primary Varietal |
| California (84.39%) (*Note: with 139 AVAs, DOMSOM will highlight only the top 20 wine producing AVAs. See below for full list of AVAs) | Central Coast | ||
| Monterey County | Cool | Pinot Noir, Chardonnay, Riesling, Sauvignon Blanc | |
| Moderate | Cabernet Sauvignon, Syrah, Merlot | ||
| San Benito County | Moderate | Chardonnay, Pinot Noir | |
| Paso Robles | Syrah, Zinfandel, Cabernet Sauvignon, Merlot | ||
| Santa Barbara | Pinot Noir | ||
| Central Valley | |||
| Central Valley (California) | Warm | Nearly all varietals – more than 75% of California grapes come from this AVA | |
| Lodi | Moderate | Zinfandel, Merlot, Syrah, Chardonnay, Sauvignon Blanc | |
| North Coast | |||
| Lake County | Warm | Cabernet Sauvignon, Syrah, Zinfandel, Sauvignon Blanc | |
| Mendocino County | Cool | Pinot Noir, Chardonnay, Riesling, Pinot Gris, Gewurztraminer | |
| Warm | Cabernet Sauvignon, Petite Sirah, Syrah, Zinfandel | ||
| Anderson Valley | Cool | Pinot Noir, Chardonnay, Riesling, Gewurztraminer | |
| Moderate | Cabernet Sauvignon, Merlot, Zinfandel | ||
| Sierra Foothills | |||
| Sierra Foothills | Warm | Zinfandel, Syrah, Barabera | |
| South Coast | |||
| Malibu Coast | Moderate | Cabernet Sauvignon, Chardonnay, Syrah | |
| San Diego County | Moderate | Cabernet Sauvignon, Chardonnay, Petite Sirah, Zinfandel | |
| Temecula Valley | Warm | Tempranillo, Syrah, Cabernet Franc, Sangiovese | |
| Washington (5.053%) | Ancient Lakes | Cool | Riesling, Chardonnay, Sauvignon Blanc, Pinot Gris |
| Columbia Gorge | Cool | Gewurztraminer, Pinot Noir, Chardonnay, Pinot Gris, Riesling | |
| Moderate | Cabernet Sauvignon, Syrah, Zinfandel, Barbera | ||
| Columbia Valley | Cool | Chardonnay, Riesling | |
| Moderate | Cabernet Sauvignon, Syrah, Merlot | ||
| Horse Heaven Hills | Cool | Riesling, Sauvignon Blanc, Pinot Gris, Chenin Blanc, Cabernet Franc, Malbec | |
| Moderate | Cabernet Sauvignon, Merlot, Syrah | ||
| Lake Chelan | Moderate | Syrah, Merlot, Pinot Noir, Gewurztraminer | |
| Naches Heights | Cool | Riesling, Cabernet Franc, Pinot Gris, Gewurztraminer | |
| Puget Sound | Cool | Pinot Noir, Pinot Gris, Muller-Thurgau | |
| Rattlesnake Hills | Moderate | Merlot, Cabernet Sauvignon, Syrah, Chardonnay, Riesling, Malbec | |
| Red Mountain | Moderate | Cabernet Sauvignon, Syrah, Merlot | |
| Snipes Mountain | Moderate | Syrah, Grenache, Viogner, Muscat, Cabernet Sauvignon, Gewurztraminer | |
| Spokane County | Warm | Merlot, Cabernet Sauvignon, Syrah | |
| Wahluke Slope | Warm | Cabernet Sauvignon, Syrah | |
| Walla Walla Valley | Moderate | Chardonnay, Gewurztraminer | |
| Warm | Syrah, Merlot, Cabernet Sauvignon | ||
| Yakima Valley | Cool | Riesling, Chardonnay, Cabernet Franc | |
| Moderate | Merlot, Cabernet Sauvignon | ||
| New York (3.468%) | Finger Lakes | Cool | Riesling, Chardonnay, Pinot Noir, Cabernet Franc, Concord, Niagara, Vidal |
| Hudson River Region | Cool | Rieling, Chardonnay, Cabernet Franc, Concord, Delaware, Niagara, Seyval Blanc, Vidal Blanc, Baco Noir | |
| Lake Erie | Moderate | Concord, Cabernet Sauvignon, Cabernet Franc | |
| Long Island | Moderate | Cabernet Franc, Merlot, Cabernet Sauvignon, Chardonnay, Sauvignon Blanc | |
| Niagara County | Cool | Riesling, Pinot Noir, Niagara, Concord, Vidal | |
| Niagara Escarpment | Cool | Riesling, Pinot Noir, Chardonnay, Niagara, Concord | |
| Pennsylvania (1.538%) | Central Delaware Valley | Cool | Chardonnay, Riesling |
| Moderate | Cabernet Sauvignon, Delaware | ||
| Cumberland Valley | Cool | Chardonnay, Cabernet Franc, Vidal Blanc, Niagara | |
| Lake Erie | Cool | Riesling, Cabernet Franc | |
| Lancaster Valley | Cool | Chardonnay, Pinot Noir, Riesling, Chamborcin, Delaware, Seyval Blanc | |
| Moderate | Sauvignon Blanc, Cabernet Sauvignon, Merlot, Cabernet Franc | ||
| Lehigh Valley | Cool | Chardonnay, Pinot Noir, Riesling, Chamborcin, Delaware, Seyval Blanc | |
| Moderate | Sauvignon Blanc, Cabernet Sauvignon, Merlot, Cabernet Franc | ||
| Oregon (1.466%) | Columbia Gorge | Cool | Chardonnay, Pinot Gris, Riesling, Pinot Noir, Chardonnay, Gewurtztraminer, Gruner Veltliner |
| Moderate | Zinfandel, Sangiovese | ||
| Columbia Valley | Cool | Chardonnay, Riesling | |
| Moderate | Cabernet Sauvignon, Syrah | ||
| Southern Oregon | Cool | Pinot Gris, Chardonnay, Riesling | |
| Moderate | Pinot Noir, Syrah, Cabernet Sauvignon, Tempranillo | ||
| Willamette Valley | Cool | Pinot Noir (Sub-AVAs: Dundee Hills, McMinnville, Eola-Amity Hills, Yamhill-Carlton District, Chehelem Mountains, Ribbon Ridge, Van Duzer Corridor) | |
| Ohio (0.736%) | Grand River Valley | Cool | Riesling, Chardonnay, Cabernet Franc, Chambourcin |
| Isle St. George | Cool | Riesling, Chardonnay | |
| Moderate | Concord, Delaware, Catawba | ||
| Lake Erie | Cool | Riesling, Gewurtztraminer, Pinot Gris | |
| Moderate | Cabernet Franc, Cabernet Sauvignon, Concord, Niagara | ||
| Loramie Creek | Moderate | Baco Noir | |
| Ohio River Valley | Cool | Chardonnay, Riesling | |
| Moderate | Cabernet Sauvignon, Cabernet Franc, Baco Noir, Seyval Blanc | ||
| Michigan (0.319%) | Fennville | Cool | Riesling, Chardonnay, Pinot Gris |
| Leelanau Peninsula | Cool | Riesling, Pinot Noir, Chardonnay | |
| Moderate | Merlot, Chambourcin | ||
| Lake Michigan Shore | Cool | Riesling, Pinot Noir, Chardonnay | |
| Moderate | Chambourcin, Concord | ||
| Old Mission Peninsula | Cool | Riesling, Chardonnay, Pinot Gris, Pinot Noir | |
| Moderate | Chambourcin | ||
| Tip of the Mitt | Cool | Pinot Noir, Chardonnay, Merlot, Riesling, Pinot Gris, Frontenac, Marquette, La Crescent | |
| Kentucky (0.270%) | Ohio River Valley | Moderate | Cabernet Franc, Cabernet Sauvignon, Chardonnay, Merlot, Riesling and Sauvignon Blanc, Catawba, Concord, Niagara, Vidal Blanc |
| Vermont (0.269%) | Vermont | Cool | Riesling, Frontenac, Seyval Blanc, La Crescent |
| Virginia (0.268%) | North Fork of Roanoke | Cabernet Franc, Merlot, Cabernet Sauvignon, Norton | |
| The Rocky Knob | Seyval Blanc | ||
| Monticello | Cabernet Franc, Cabernet Sauvignon, Petit Verdot, Merlot, Malbec, Chardonnay, Viognier, Sauvignon Blanc, Riesling | ||
| George Washington Birthplace | Moderate | Cabernet Franc, Chardonnay, Vidal Blanc and Chambourcin | |
| Eastern Shore | Moderate | Cabernet Franc, Chardonnay, Merlot | |
| Peninsula | Moderate | Tannat, Petit Verdot, Cabernet Sauvignon, Merlot, Norton, Viogner, Albarino, Chardonnay, Sauvignon Blanc | |
| Middleburg | Cabernet Franc, Cabernet Sauvignon, Petit Verdot, Merlot, Chardonnay, Viognier, Sauvignon Blanc | ||
| Shenandoah Valley | Cabernet Franc, Cabernet Sauvignon, Petit Verdot, Merlot, Malbec, Chardonnay, Viognier, Sauvignon Blanc, Riesling | ||